Eventually, its time to find a sweeper, and I have to play the game of choosing between tier 2 options like Rolling Temblor, Blasphemous Act, Magmaquake, and Damnation (tier 2 once it destroys the mana base)
You could make a token copy of Deadpool, have the token exchange its text box with an opponent's creature, and the opponent's creature will exile itself at the end of combat (and you'll get to keep your nonlegendary Deadpool token)
Basically, any deck trying to play fair midrange Magic has a tough time preventing you from completing your plan
It's not enough to make the cut in 60-card formats, but this red instant is massively popular in casual Commander and sees plenty of cEDH play
Butcher Ghoul Demonlord of Ashmouth Endling Evernight Shade Flayer of the Hatebound Garbage Elemental Geralf's Messenger Geralf's Mindcrusher Gleeful Arsonist Hancock, Ghoulish Mayor Haunted One Hound of Griselbrand Howlgeist Mikaeus, the Unhallowed Nardole, Resourceful Cyborg Nearheath Stalker Phyrexian Midway Bamboozle Pyreheart Wolf Relentless Skaabs Shadow of the Goblin Sightless Ghoul Stormbound Geist Strangleroot Geist Treacherous Pit-Dweller Undying Beast Undying Evil Undying Flames Undying Rage Vengeful Vampire Vorapede Witch-king, Sky Scourge Yahenni, Undying Partisan Young Wolf