Human FcRn GST Amount:250 µg Goeddel (2002)

Goeddel (2002)

The extracellular CRD regions of the TNFR2 and TNFR1 are quite similar

overexpression of TRAIL-R3 prevents TRAIL-sensitive cells from apoptosis and cells can be re-sensitized by phospholipase treatment –consistent with the notion that TRAIL-R3 is GPI-anchored

A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function

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Human FcRn GST Amount:250 µg Goeddel (2002)Human neonatal Fc receptor (FcRn) was named for its role in transferring IgG molecules across placenta to the fetus. Structurally, it is distinct from the classical IgG receptors for its similarity to the MHC class I instead of the Ig superfamily (IgSF) molecules. Binding of FcRn to IgG protects the latter from being proteolytically attacked by the endocytic lysosomal enzymes. The preservation of the antibody molecules by FcRn is central to the